CDMRP: Breast Cancer (BC) Research Program – Pre-applications

Overarching Challenges

• Prevent breast cancer (primary prevention)
• Identify determinants of breast cancer initiation, risk, or susceptibility
• Distinguish deadly from non-deadly breast cancers
• Conquer the problems of overdiagnosis and overtreatment
• Identify what drives breast cancer growth; determine how to stop it
• Identify why some breast cancers become metastatic
• Determine why/how breast cancer cells lie dormant for years and then re-emerge; determine how to prevent lethal recurrence
• Revolutionize treatment regimens by replacing them with ones that are more effective, less toxic, and impact survival
• Eliminate the mortality associated with metastatic breast cancer
• Alternatively, with adequate justification, applications may identify and address another overarching challenge"

Funding mechanisms:

Clinical Research Extension Award: $5M for 4 years.

https://ebrap.org/eBRAP/public/ProgramFY.htm?programFYId=413101

https://ebrap.org/eBRAP/public/ViewFileTemplate.htm?fileTemplateId=10063236&fileType=pdf