MPN Research Foundation: Myeloproliferative Neoplasms Research

The primary goal of the MPN Research Foundation’s research strategy is:

1) accelerate access to high quality, effective and even curative therapies for people living with MPNs and

2) to understand and control the progression of the MPNs from chronic to life-threatening stages.

particular interest in this cycle are:

1. Early detection of MPNs – Proposals that focus on early detection and understanding of disease trajectory including hematopoietic stem cell studies and clonal evolution and studies that describe the selective pressure that may drive CHIP to overt MPNs.
2. Understanding thrombotic/cardiovascular risk in MPN patients – Proposals that address risk factors and new treatment strategies.
3. Role of epigenomic factors in MPNs – Proposals focusing on epigenomic factors and their role in the natural history of MPNs.
4. Role of environmental factors in MPNs – Proposals focusing on environmental factors and their role in the natural history of MPNs.
5. New mechanisms of action - Proposals for basic research and preclinical testing of new and innovative mechanisms of action (e.g., new targets or pathways) other than the common driver mutations associated with MPNs.
6. Quality of life research – Proposals focusing on research to further understand disease symptom burden and its impact on the quality of life for patients with MPNs.

Funding: up to $100,000 per year with a potential total of up to $200,000 over 2 years.

https://files.constantcontact.com/99e3e2da001/319a9560-d01e-4d47-bd47-c49bdba3523e.pdf

https://forms.zohopublic.com/tdavis1/form/2021MPNCHALLENGEAPPLICATION/formperma/odChAu0P3R7qNbvZ3mIjlSvSTY2OKad_x8a4_TZQ7Po