Orphan Disease Center and LouLou foundation: CDKL5 Pilot Grant Program - One page LOI

 

The ODC and Loulou Foundation CDKL5 Pilot Grant Program supports research related to CDKL5 Deficiency Disorder (CDD). Projects directed toward the development of treatments or a cure for CDKL5 deficiency, a monogenic, orphan condition characterized by treatment-resistant epilepsy and severe cognitive and motor disability, as well as basic science projects that address the gaps in the basic understanding of CDKL5 and its role in neurologic development are required.

Grants should cover the following areas:
1) Novel therapeutic approaches for CDD
2) Validation of phenotypes in CDKL5 function or disease pathophysiology 
3) Systems biology and computational modeling approaches
4) Novel application of imaging and functional techniques 
5) Discovery and validation of CDKL5 biomarkers 

Funding: 150,000 for one year.

Nonprofit. Overhead 10% in exceptional cases -  please contact Research Authority if planning to submit.

http://orphandiseasecenter.med.upenn.edu/uploads/attachments/cjrqpxp9l1yozxltu8z3qa99z-2019-cdkl5-funding-opportunity-final.pdf