Pancreatic Cancer Action Network-AACR: Research Acceleration Network Grant - LOI

Objective: improving the detection or treatment of pancreatic cancer.
Possible scenarios include, but are not limited to:
*An immunotherapy approach that clinically tests combinations of a previously-tested vaccine with one or several immune modifying factors;
*Preclinical testing of rational combinations of chemotherapeutic agents currently in early phase clinical development and initial combination clinical trials;
*Neoadjuvant clinical study with tumor tissue for predictive and/or pharmacodynamic marker development;
*Adaptive clinical trial incorporating multiple targeted agents and predictive biomarkers;
*Clinical bioavailability studies for a promising imaging agent and the initiation of studies in a high-risk cohort;
*Large retrospective study with samples from multiple sites for an early detection or predictive serum biomarker panel with a feasible strategic plan for a prospective study.
Project must include a clinical component (implemented at least by year 3).
Project must be implemented by a multi-institutional team. The applicant designated as the contact PI must be affiliated with an institution within the United States. Co-PIs can be affiliated with any institution in the world.
Funding: $1,000,000 over 1-3 years. At least 1 project will be funded.
http://www.aacr.org/Funding/Pages/Funding-Detail.aspx?ItemID=35#.VAV9SMV_s-M