ALS Association: Clinical Management and Research

a. Clinical Research Pilot Study: This request for proposals seeks to fund pilot clinical studies to obtain preliminary clinical data which will support applications to the National Institutes of Neurological Disorders and Stroke (NINDS) for subsequent larger clinical trials of an intervention to treat or prevent ALS. The proposed study must address questions that, when answered, will optimize the design of more definitive clinical trials rather than simply addressing the clinical question with lower power. The research proposal should directly address how the preliminary study will advance the design of a subsequent definitive clinical trial for efficacy. Funding: max $150K/year for max 2 years.
b. Clinical Management Grants: The aim of the Program is to improve care and living with ALS with a focus on clinical, psychological and/or social management of ALS. Examples of relevant clinical management studies for this mechanism include, but are not limited to, the following:
•Studies that address the gaps in the delivery of care (as outlined in the ALS practice parameters).
•Studies that explore and develop telemedicine for the care of individuals with ALS.
•Psychological interventions in ALS to address the significant mental health issues facing ALS patients and care givers.
•Nutritional and respiratory intervention.
•Studies to address the needs of care givers for patients with ALS and cognitive/behavioral impairment.
Funding: max $100K/year for a max 2 years.
http://www.alsa.org/news/archive/rfa-clinical-research.html