CurePSP: Research Grants in Progressive Supranuclear Palsy (PSP) and Corticobasal degeneration (CBD)

CurePSP promotes research that helps generate an integrated picture of PSP and CBD at the molecular and cellular levels.
Funding: Up to $300,000 over 3 years.  Particular interests:
1. Understand the role of the tau gene and other genes in PSP and CBD.
2. Understand the role of tau protein processing in PSP and CBD.
3. Understand cellular energy metabolism and oxidative stress perturbations in PSP and CBD.
4. Understand environmental factors that influence the development or course of PSP and CBD.
5. Understand the series of changes brain cells pass through in PSP and CBD as they progress from healthy neurons to dysfunctional neurons.
6. Characterize the natural history of PSP and CBD in order to develop outcome measures for clinical trials.
7. Develop animal models of PSP and CBD.
8. Develop tools and disease markers for early diagnosis of PSP and CBD and for assessment of treatment.
9. Develop treatments that improve the symptoms of persons with PSP and CBD.
10. Develop interventions to arrest the progression of PSP and CBD and restore lost function.